Case Study 1: Innovative compound repurposing
An innovative compound with low efficacy but good safety profile was received from client originally indicated for osteoporosis. Using GVK BIO repurposing integrated platform a novel mechanism of action was identified and the compound was proposed for TB & Pulmonary hypertension with novel first in class mechanism of actions
Case Study 2: Generic Drug repurposing
A generic drug company approached for identifying repurposing opportunities for known marketed drug with current clinical use in CNS disorders. Scientists at GVK BIO have proposed this drug for hearing loss & cystic fibrosis with new route of administration.
Case Study 3: Failed compound
A failed compound with lack of efficacy but good safety profile was received from client originally indicated for Alzheimer’s disease. Neither the mechanism of action nor the target profile was known for this compound. Using compound proprietary data and GRIP, GVK Bio scientist proposed retinal degeneration as possible alternative indication.