GVK BIO is the PDP Preferred Partner
The Global Health Product Development Partners Consortium has chosen GVK BIO to be a preferred partner. The only partner headquartered in India, we will be one of the 14 global Product Development Partners (PDPs) for clinical services in Asia, collaborating with the consortium as a niche service provider for clinical and safety monitoring, logistics support and overall project management.
The PDPs, funded in part by the Bill and Melinda Gates Foundation, are not-for-profit entities focused on developing new interventions for diseases such as tuberculosis, malaria, kala-azar, HIV/AIDS, childhood pneumonia, and diarrheal diseases, that are often neglected by mainstream pharmaceutical and biotech companies. Collectively the 14 PDPs anticipate funding 85 clinical trials in the developing world over the next two years and India features as a key developing world country.
Biomarkers in demand
The Informatics division of GVK BIO recently partnered with the Indiana Clinical and Translational Sciences Institute (CTSI) to provide researchers across the United States access to GVK Biosciences Clinical Biomarker Database (GOBIOM). The GOBIOM is a comprehensive collection of all clinically evaluated, exploratory and preclinical biomarkers associated with different therapeutic areas reported in global clinical trials, clinical and preclinical studies. CTSI believes that it is a powerful tool for clinicians and researchers looking to mine the most up-to-date and comprehensive information about any putative biomarker for personalized therapeutics. This database was developed in collaboration with the US Food and Drug Administration (USFDA). Earlier on this year, the GOBIOM license was even extended to the Biomarker Qualification Group of the USFDA.
Scientific Recognition: Eli Lilly and Company Asia Outstanding Thesis Award 2010
Dr Amit Kumar of Chemistry Services, Nacharam received the Eli Lilly and Company Asia Outstanding Thesis Award, 2010, First Prize, with a cash prize of $1500 at a ceremony held at the 6 J NOST Conference at the University of Hyderabad on 28th January, 2011.
Instituted in 2009, the award includes 20 selections, 10 for the first prizes and 10 for the second prizes, from various IITs, CSIR institutes and Universities across India.
Analytical Services strengthened – new Service Line created
GVK BIO now provides analytical and separation services to support lab chemistry, discovery and process chemistry.
Dr K S V Srinivas, with over 18 years of Analytical R&D experience, heads the efficient and professional Analytical Services unit. The labs are well-equipped with various state-of-the-art instruments, such as LC/MS, HPLC, GC/MS, SFC, NMR, FTIR, etc.
Our full range of analytical services include:
- Analytical method development
- Validation of analytical procedures
- Analytical Method Transfer Exercise (AMTE)
- Isolation and purification – Chiral & Achiral
- Impurity characterization
- Particle size analysis & validation
- Stability studies (ICH Conditions)
- Microbiology testing
- Spectroscopic studies-1H NMR, 13C NMR and other nuclei
For further information write to email@example.com
Launching Library Design and Synthesis
The Library Design and Synthesis service at GVK BIO is dedicated to designing, synthesizing and analyzing a wide range of small organic molecule libraries for a variety of targets, including kinases and other enzymes, GPCRs, ion channels, and nuclear receptors. The library can be designed based on client ideas, or our knowledge of synthesizing libraries.
We enumerate the designed compounds by using different tools and screen the libraries for desirable properties such as Lipinski, Drug likeness, Lead likeness, Veber filters, Muegge filters and Ghose filters among others. Other properties that can be used to sort the compounds are logD, heavy atom count, rotatable bond count, ring count, and fused aromatic ring count, to suit client requirements.
We can also work with computational chemists of our Informatics division to provide focused libraries for specific targets. Such focused libraries can be specifically designed based on customers’ data and requirement. Selective synthesis of part of a library is also possible. In our experience it g