Mr. Kiran Kumar joins as President, Inogent Labs

Mr. Kiran Kumar joins as President, Inogent Labs We are pleased to inform you that Mr. R Kiran Kumar has taken over as President, Inogent Labs, a GVK BIO company. Kiran reports in to the CEO of GVK Biosciences, Mr. Manni Kantipudi. Kiran holds a Masters in Chemical Engineering and has 25 years of experience in the pharmaceutical industry and API research. Prior to joining GVK BIO, he was the Chief Operating Officer of Astrix Labs, Hyderabad. Kiran has also held leadership positions in companies like Dr Reddy’s Labs, Jubilant Organosys, Siris Limited and Matrix Labs.

Inogent Labs, is a GVK BIO company, based out of Hyderabad, India and is ISO 9001 & WHO cGMP certified. Inogent offers an attractive mix of Services (Process R&D and Custom Chemical Synthesis & Manufacturing) and Products (APIs and Intermediates) to its clients.

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Celebrating successful synergies – GVK BIO turns 10


On April 2, 2011, GVK BIO turned 10. These 10 years have been possible only due to the strong associations and lasting relationships we’ve built with our clients, partners and collaborators – which is why they were as much a part of our celebrations as our employees. Many of them even joined us by participating in our scientific seminars.

Here’s to many more years of great partnerships!

“Over the last nine years our relationship with you has grown from a place to test ideas to a trusted partner that is an important contributor to the success of our new product pipeline. As an employee of DuPont, a more than 200 year old company, I wish GVK BIO the same longevity and success. Congratulations on your ten year anniversary”.

Bill Barnette,
Manager, Chemical Discovery


“These days collaborations are getting more and more important to many corporations and DuPont Crop Protection is no exception. Because of the nature of the changes that are going on in the world today, collaboration is particularly important to take advantage of a global work force for a global company such as DuPont. I would like to thank the entire GVK BIO-DuPont team and their group leaders for their dedication and hard work in delivering the projects on time and contributing to the success of our discovery process. Special thanks to Satya for staying with the team for the past 9 Years and leading the group the last 7 years”.

Bal Kamireddy,
Alliance Manager, Discovery Chemistry


DuPont: Progress in the Discovery of New Products for Insect Control

DuPont: Progress in the Discovery of New Products for Insect Control -
Dr George Lahm, Distinguished Scientist
Dr Balreddy Kamireddy, Alliance Manager
Dr Joel Christensen, Manager Insecticide Chemistry

Use of CADD methods and Structural Biology for the Discovery of Novel Clinical Candidates

Use of CADD methods and Structural Biology for the Discovery of Novel Clinical Candidates
Dr Rami Reddy

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GVK BIO is the PDP Preferred Partner


GVK BIO is the PDP Preferred PartnerThe Global Health Product Development Partners Consortium has chosen GVK BIO to be a preferred partner. The only partner headquartered in India, we will be one of the 14 global Product Development Partners (PDPs) for clinical services in Asia, collaborating with the consortium as a niche service provider for clinical and safety monitoring, logistics support and overall project management.

The PDPs, funded in part by the Bill and Melinda Gates Foundation, are not-for-profit entities focused on developing new interventions for diseases such as tuberculosis, malaria, kala-azar, HIV/AIDS, childhood pneumonia, and diarrheal diseases, that are often neglected by mainstream pharmaceutical and biotech companies. Collectively the 14 PDPs anticipate funding 85 clinical trials in the developing world over the next two years and India features as a key developing world country.

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Biomarkers in demand


Biomarkers in demandThe Informatics division of GVK BIO recently partnered with the Indiana Clinical and Translational Sciences Institute (CTSI) to provide researchers across the United States access to GVK Biosciences Clinical Biomarker Database (GOBIOM). The GOBIOM is a comprehensive collection of all clinically evaluated, exploratory and preclinical biomarkers associated with different therapeutic areas reported in global clinical trials, clinical and preclinical studies. CTSI believes that it is a powerful tool for clinicians and researchers looking to mine the most up-to-date and comprehensive information about any putative biomarker for personalized therapeutics. This database was developed in collaboration with the US Food and Drug Administration (USFDA). Earlier on this year, the GOBIOM license was even extended to the Biomarker Qualification Group of the USFDA.

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Scientific Recognition: Eli Lilly and Company Asia Outstanding Thesis Award 2010

HeaderDr Amit Kumar - Scientific Recognition: Eli Lilly and Company Asia Outstanding Thesis Award 2010
Dr Amit Kumar of Chemistry Services, Nacharam received the Eli Lilly and Company Asia Outstanding Thesis Award, 2010, First Prize, with a cash prize of $1500 at a ceremony held at the 6 J NOST Conference at the University of Hyderabad on 28th January, 2011. Instituted in 2009, the award includes 20 selections, 10 for the first prizes and 10 for the second prizes, from various IITs, CSIR institutes and Universities across India.

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Analytical Services strengthened – new Service Line created

Analytical Services strengthened – new Service Line createdGVK BIO now provides analytical and separation services to support lab chemistry, discovery and process chemistry. Dr K S V Srinivas, with over 18 years of Analytical R&D experience, heads the efficient and professional Analytical Services unit. The labs are well-equipped with various state-of-the-art instruments, such as LC/MS, HPLC, GC/MS, SFC, NMR, FTIR, etc.

Our full range of analytical services include:

  • Analytical method development
  • Validation of analytical procedures
  • Analytical Method Transfer Exercise (AMTE)
  • Isolation and purification – Chiral & Achiral
  • Impurity characterization
  • Particle size analysis & validation
  • Stability studies (ICH Conditions)
  • Microbiology testing
  • Spectroscopic studies-1H NMR, 13C NMR and other nuclei

For further information write to bdmcl@gvkbio.com

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Launching Library Design and Synthesis

The Library Design and Synthesis service at GVK BIO is dedicated to designing, synthesizing and analyzing a wide range of small organic molecule libraries for a variety of targets, including kinases and other enzymes, GPCRs, ion channels, Launching Library Design and Synthesisand nuclear receptors. The library can be designed based on client ideas, or our knowledge of synthesizing libraries.

We enumerate the designed compounds by using different tools and screen the libraries for desirable properties such as Lipinski, Drug likeness, Lead likeness, Veber filters, Muegge filters and Ghose filters among others. Other properties that can be used to sort the compounds are logD, heavy atom count, rotatable bond count, ring count, and fused aromatic ring count, to suit client requirements.

We can also work with computational chemists of our Informatics division to provide focused libraries for specific targets. Such focused libraries can be specifically designed based on customers’ data and requirement. Selective synthesis of part of a library is also possible. In our experience it g