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Products & Services / Biology Services

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Biology Services

 

In Vitro Biology ADME PK/PD Studies Safety Pharmacology
  • Reagent generation
  • Assay development
    and screening
  • Specialized cell based assays
  • High throughput screening
  • Physicochemical studies
  • Absorption / distribution assays
  • Metabolic stability
  • Bioanalysis
  • In vivo PK
     
  • Animal models
    • Pain
    • Inflammation
  • Exploratory toxicity
  • Side effect profiling
  • Primary/Functional screening
  • Selectivity profiling
  • In vitro ADMET
  • In vivo efficacy/PK/Exploratory
    toxicology

HIT

IND Candidate

  • Hit generation
  • Hit Validation
  • Lead optimization
  • Drug candidate

Biological assessment of New Molecular Entities (NMEs) plays a crucial role in ascertaining structure activity relationships, potency, selectivity, drugability and in vivo efficacy evaluation.

The scope of Biology services at GVK BIO encompasses in vitro and in vivo profiling of molecules for their activity, potency, efficacy, ADME and toxicity. In order to gain from our service offerings an increasing base of pharmaceutical companies worldwide is turning to GVK BIO for its outsourcing needs in Biology.

In addition to Biology standalone services, one of the principal benefits to our clients is our Integrated Services Platform. This allows access to multiple and seamless outsourcing choices across the drug discovery chain, ensuring speedy implementation of their research projects. They also stand to benefit from the fact that the Biology services at GVK BIO complement our strengths and capabilities in other departments, like Medicinal Chemistry, Informatics and Clinical Research. Capitalizing on our Biology strengths, our clients have advanced their early discovery programs. They have accelerated their research, and built and developed a strong pipeline, in a short span of time.

We offer a complete solution to meet the requirements of our customers. Our In Vitro Biology services include Reagent Generation services, Assay Development services and High throughput screening services. We also provide custom tailored In Vitro Pharmacology, ADME and PK solutions. Our state-of-the-art infrastructure enables us to provide clients In Vitro Services, In Vivo PK studies, ADME and Toxicity services under one roof. GVK BIO extends a wide range of ADME services where we offer cost-efficient standardized and customized assays as per the client’s requirement for ADME parameters.

We perform experimental models in rodents, in the therapeutic areas of Inflammation, Pain and others, to determine efficacy of a compound. The GVK BIO vivarium is AAALAC certified and registered with CPCSEA.