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Products & Services / Infrastructure

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Infrastructure

To facilitate quality research and ensure timely delivery, the Biology facility at GVK BIO is equipped with state-of-the-art instrumentation, modern infrastructure and cutting edge processes. The infrastructure comprises various laboratories viz., the wet experimental area, approved hot labs for working with Radioactive Isotopes, laboratories with analytical instruments and a fully equipped, high-maintenance, Cell Culture lab. Our facilities are built to support the research work done by our organization.

Radioactive Lab

  • State-of-the-art AERB India accredited “Type III lab”
  • Permission to handle 14C, 3H, 32P, 33P, 35S, 125I, 51Cr
  • Semi-automated assay platform – Microbeta Top Count (384 & 96 well) with 12 detectors

Cell Culture Lab 

  • Equipped to support radioactive and fluorescent based enzyme assays
  • Envision, BMG Polastar, Spectramax UV/VIS spectrophotometer, Fluorescence Imaging
  • Biomek Fx & Nx, and Tomtec Liquid Handling and Sample preparation system
  • Well-established P2 cell culture lab equipped with Laminar flow hoods, CO2 incubators, wave bioreactor, multidrop dispenser, etc.
  • Repository of cell lines maintained (transformed and recombinant)

Molecular Biology Lab

  • Fully equipped lab to perform cloning, bacterial culture, protein expression and purification
  • Gel imaging system, wave bioreactor
  • ABS Gradient PCR, AKTA FPLC System, etc.
  • High speed centrifuge, freeze dryer (Lyophllizer)
  • Freezers (-80˚C and -20˚C)

Animal Pharmacology

  • AAALAC accredited facility
  • In-house facility for rodent equipped IVC cages and study for in-life PK and animal model
  • Registered with CPCSEA (Committee for the Purpose of Control and Supervision of Experiments on Animals), Government of India
  • Spontaneous Locomotor Activity Meter, Tail Suspension Test, Plantar, Plantar Von Frey, Hot Plate, Tail Flick, Transonic ECG, BP & Blood Flow Meter with Emka Software
  • Gas Anaesthesiometer, Vernier Calipers, Water Plethysmometer, Glucometer, Graphpad software for statistical analysis

DMPK and Bioanalytical Lab

  • Bioanalysis: LC-MS/MS
  • SCIEX-4000 with HTS-PAL Autosampler and Agilent 1200 HPLC
  • SCIEX-3200 Q trap with Agilent 1200 HPLC with PDA detector
  • SCIEX-3000 with Shimadzu Prominence with UV detector
  • Spectramax Plus 384 spectrophotometer by Molecular Devices and Fluorescence reader
  • Radioactivity Count by Top Count (Perkin Elmer)
  • Biomek Fx & Nx, and Tomtec Liquid Handling and Sample preparation system
  • Watson LIMS and WinNonlin