Also, Protac, Nucleotides, Nucleosides, Peptides, Proteins, Biomarkers
Protein fingerprinting protein work flow (Integral mass identification, peptide mapping, glycan analysis, estimations; separation and estimation of deuterated Enantiomers. For quantitative bioanalyses about 100 microl of matrix is required with a turnaround time of 3 days.
Any study including mass spectrometry (MS) assays (such as stability, permeability, protein binding) requires both molecular weight (MW) and formula weight (FW) of each tested compound, even if they are the same. The FW is required to prepare the stock solution of each compound at the correct concentration. The MW gives indication on which expected molecular ion to look for in our LC-MS screen assay.
Using advanced LC-MS-based techniques for metabolite profiling and structural identification, the Met ID team works in tandem with the entire DMPK unit to provide the information you need to take your compound from concept to candidate.