Cosmetics
Solutions

We care for your safety

GVK BIO offers solutions for cosmeceutical formulation efficacy and safety evaluation for various purposes like skin care, hair care and anti-aging. Various in-vitro and cell-based assay platforms have been developed in-house to assess the efficiency of active molecules viz., ELISAs, bioassays, cell based assays, protein profiling and genomic profiling.

Offerings:

Skin Care

• Melanin pigment estimation assay using melanoma cell lines
• Melanin transfer assay using co-culture studies
• Tyrosinase inhibition assay
• MC1 receptor binding assays using primary melanocytes
• Reconstituted 3D in vitro model for melanin estimation

Hair Care

• 5α reductase inhibition assay
• Cell based hair growth factors (IGF, VEGF, KGF and TGFβ) estimation assay
• Proteomic and gene profiling of marker proteins

Anti-Ageing

• Co-culture studies to assess collagen levels
• Evaluation of matrix metalloproteinases inhibitions
• Estimation of the epidermal marker involucrin release
• Elastase inhibition assay

Toxicity & Safety Evaluations

• Cytotoxicity assays
• Phototoxicity assay using neutral red
• Cutanious irritation using 3D reconstituted human epidermis
• Skin corrosion using 3D reconstituted human epidermis
• Corneal irritation using 3D corneal epithelium model
• Alternate for animal testing (3D cell culture assays)