We care for your safety
GVK BIO offers solutions for cosmeceutical formulation efficacy and safety evaluation for various purposes like skin care, hair care and anti-aging. Various in-vitro and cell-based assay platforms have been developed in-house to assess the efficiency of active molecules viz., ELISAs, bioassays, cell based assays, protein profiling and genomic profiling.
Offerings:
Skin Care
- Melanin pigment estimation assay using melanoma cell lines
- Melanin transfer assay using co-culture studies
- Tyrosinase inhibition assay
- MC1 receptor binding assays using primary melanocytes
- Reconstituted 3D in vitro model for melanin estimation
Hair Care
- 5α reductase inhibition assay
- Cell based hair growth factors (IGF, VEGF, KGF and TGFβ) estimation assay
- Proteomic and gene profiling of marker proteins
Anti-Ageing
- Co-culture studies to assess collagen levels
- Evaluation of matrix metalloproteinases inhibitions
- Estimation of the epidermal marker involucrin release
- Elastase inhibition assay
Toxicity & Safety Evaluations
- Cytotoxicity assays
- Phototoxicity assay using neutral red
- Cutanious irritation using 3D reconstituted human epidermis
- Skin corrosion using 3D reconstituted human epidermis
- Corneal irritation using 3D corneal epithelium model
- Alternate for animal testing (3D cell culture assays)