Safety & Toxicology

CNS Safety

  • Tail suspension test in mice
  • Spontaneous locomotor activity measurement in rats
  • Rotorod testing in rats and mice

Genotoxicity

  • Mini Ames/Complete Ames
  • Mouse Lymphoma Assay
  • Chromosomal Aberration
  • Micronucleus Test

Exploratory Toxicity

  • Acute toxicity/maximum tolerated dose (MTD)
  • Repeat dose 7-90 Days Toxicity
  • Toxicokinetics (TK)
  • Histopathology (with a partner)

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