Nucleoside & Nucleotide Synthesis
We have well established capabilities in synthesising nucleoside and nucleotides with modification in sugar and base moieties. We have expertise in synthesising modified amino sugar, halogenated sugars, S & N containing monosaccharides, chiral lactones, neuraminic acid and glycosidation with non-carbohydrate moieties.
In addition, nucleoside based complex building blocks have been synthesised and used for focused library generation. All compounds are characterised by extensive analytical studies like 1H, 19F, 31P-NMR, LCMS and HPLC. Nucleosides / nucleotides are purified through chiral and SFC-purification technique as required.