Psoriasis is a type of disease where the immune system of the body attacks the skin itself. It speeds up the life cycle of the skin which causes a massive buildup of cells on the surface of the affects portion of the skin
- Plaque Psoriasis – Is also called as psoriasis vulgaris, it is the most common type of psoriasis The skin surface looks raised, red patches covered with a silvery white buildup of dead skin cells or scale. This usually appear on the scalp, knees, elbows and lower back. They are often itchy & painful and upon cracking it bleed.
- Guttate Psoriasis – It often starts appearing at a very young age in the childhood or young adulthood. This condition is the second most common type of psoriasis. This type of psoriasis appears as small, red, and unevenly distributed spots on the skin. In this type of psoriasis, the thickening of the skin is less when compared to plaque psoriasis.
- Inverse Psoriasis – It is also called as intertriginous psoriasis; this type of psoriasis usually effects the skin folds (where the skins rubs against the skin) all across the body. It causes smooth patches of red, inflamed skin that worsen with friction and sweating. Fungal infections may the trigger for it.
- Pustular Psoriasis – This is the most uncommon type of psoriasis and usually occurs in adults. It causes pus-filled bumps (pustules) surrounded by red skin. These may look infectious, but are not. It may show up on one area of your body, such as the hands and feet. Sometimes it covers most of your body, which is called “generalized” pustular psoriasis. When this happens, it can be very serious, so get medical attention right away.
- Erythrodermic Psoriasis – It affects most of your body and causes widespread, fiery skin that appears to be burned. It is a rare type of psoriasis and a form of aggravated inflammation. In patients with psoriasis, there is an overproduction of T cells.
- Nail Psoriasis – It usually happens on the nails, it is common with people who have psoriatic arthritis, which affects the joints. The nails may get thick, develop pinprick holes and change color or shape. They also can feel tender and hurt.
- Psoriatic arthritis – Is a condition where you have both psoriasis and arthritis. In most of the cases, people have psoriasis for about 10 years before getting psoriatic arthritis. About 90% of people with it also have nail changes.
GVK BIO provides IMQ induced preclinical psoriasis model for drug discovery.