Drug Discovery

Innovation-driven collaborations to accelerate your discovery programs

GVK BIO utilizes its expertise in medicinal chemistry, CADD, DMPK, In Vitro and In Vivo models to provide customized integrated Drug Discovery Solutions leading to preclinical candidates. Our strong scientific team works closely with clients to select and execute the most promising strategy to deliver project goals in the shortest possible time.

  • 25+ integrated programs with big pharma/biotech /virtual companies
  • Delivered 1 clinical and 7 preclinical candidates
  • Inventors on 25+ patents and 4 publications in the last 7 years
  • Our medicinal chemists work in collaboration with a strong group of 1000+ synthetic chemists
  • A team of 100+ biologists (India and USA) routinely assist collaborators with protein production, assay development, DMPK and In Vivo disease models
  • Secured IT infrastructure with Websense Triton APX DLP implemented to protect against advanced threats and data theft
  • Flexible business models and ability to quickly scale-up infrastructure and skilled manpower as per requirements

We provide Integrated Drug Discovery solutions ranging from hit identification, lead generation and lead optimization to an optimized preclinical candidate for development.

Hit Identification

Virtual Screening, High-throughput screening on commercial / client provided library and knowledge-based design

Lead Generation and Multi Parameter Optimization (MPO):

Identification of potent and selective compounds with desirable PK parameters

Lead Optimization

Optimization of potency, PK, efficacy and safety profiling to deliver a pre-clinical candidate

GVK BIO has developed an expertise in the area of:




Cardio Metabolic


  • Project feasibility
  • Reference compound synthesis and profiling
  • Assay development for potency and ADME
  • Virtual library design


  • Medicinal chemistry
  • Computational chemistry
  • In Vitro potency
  • Selectivity
  • In-depth ADME, PK, In Vivo efficacy
  • Exploratory Tox

Regulatory Studies

  • Patent filing
  • GLP/GMP manufacturing: USFDA, PMDA
  • Metabolism
  • Met ID characterization


Integrated Drug Discovery Solutions

Download the Brochure


Pharmacokinetic Strategies in CNS Drug Discovery

Download the Whitepaper
Get in Touch With Our Scientific Team