Animal Models
of Metabolic
Disease

Animal Models of Metabolic Disease

GVK BIO offers a number of rodent models in the area of diabetes, obesity, NASH and fibrosis. We house all our animals in individually ventilated cages, which offer the option of conducting long term chronic studies without any impact on the animals’ health. We do have access to genetic diabetic rodents which can be procured for studies.

Obesity

  • Corn Oil-induced Dyslipidemia
  • Intralipid-induced Dyslipidemia
  • Ghrelinemia model
  • Diet Induced Obesity (DIO)

Non-alcoholic steatohepatitis (NASH)

  • Streptozotocin (STZ) + High fat diet (HFD)-induced NASH
  • AMLN (Amylin Liver NASH) model in mice

Kidney Disease (CKD)

  • Adenine-induced CKD
  • Streptozotocin (STZ) + High fat diet (HFD)-induced diabetic nephropathy
  • Unilateral ureteral obstruction (UUO)

Cardiovascular

  • Monocrotaline-induced Pulmonary Arterial Hypertension (PAH)
  • Bleeding model in rats

Brochure

In Vivo Pharmacology

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Whitepaper

In Vivo Models & In Vitro Assays for Human RSV Infection - Pre-Clinical Antibody, Small Molecule & Vaccine Development

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