Targeted
Protein
Degradation
(TPD)

Combining our deep expertise in chemistry and biology, we at GVK BIO have helped accelerate the development of several targeted protein degraders (PROTACs and Molecular Glues) for our global customers, and have helped solve several scientific problems in this exciting new field.


How can GVK BIO Accelerate your TPD Program?

  • Experience with multiple degrader technologies: PROTAC and Molecular Glue
  • A continuum of chemistry, assay development and screening, DMPK, in vivo efficacy, and exploratory toxicology to accelerate your TPD program
  • Experience with optimizing ADME/PK properties and formulations for PROTACs and Molecular Glues
  • Established primary pharmacology screens for TPD
  • XLRATE™ Project Management to integrate Chemistry and Biology (in vitro and DMPK) all in one location